Medical Journal of Malaysia

MJM, Vol 70 Supplement 1 September 2015

Predictors for quality of life of chronic kidney disease and end stage renal disease patients in Kelantan

Farzaana Adam*, Ab Aziz Al-Safi Ismail*, Syed Hatim Noor**, Azreen Syazril Adnan***

*Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, **Unit of Biostatistic and Research Methodology, School of Medical Sciences, Universiti Sains Malaysia, ***Chronic Kidney Disease Research Centre, School of Medical Sciences, Universiti Sains Malaysia


Introduction: Optimising the Quality of life of Chronic kidney diseases (CKD) patients are vital as they required lifelong follow up and to prevent deterioration to end stage renal disease (ESRD).  The objective of this study is to determine the predictors of the Overall Health Scale of CKD stage 3, pre-dialysis, and ESRD patients. 

Methods: Cross-sectional study at four hospitals in Kelantan. Non dialysis cases at the Nephrology Clinic recruited through simple random sampling, whereas, all cases on dialysis which fulfilled the inclusion criteria were included. A translated Malay version of Kidney Disease Quality of Life Questionnaire Short Form (KDQOL-SF) questionnaire were used in the interviews. 

Results: There were 55 CKD stage 3, 100 pre-dialysis and 152 ESRD cases.  Presence of cardiovascular disease predicted the Overall Health Scale in CKD stage 3 patients (adjusted β: -20.00; 95%CI: -33.47, -6.53). Predictors in pre-dialysis patients were presence of dyslipidaemia (adjusted β: 12.10; 95%CI: 3.96, 20.24),  body mass index (adjusted β: -0.09; 95%Cl: -1.74, -0.14) and glomerular filtration rate (adjusted β: 0.56; 95%Cl: 0.18, 0.95); whereas the predictors in ESRD patients were employment status (adjusted β: -8.79; 95%Cl: -13.96, -3.63), presence of diabetes (adjusted β: -5.58; 95% Cl: -10.83, -0.34), age (adjusted β: -0.22; 95%Cl: -0.42, -0.03), haemoglobin level (adjusted β: 2.38; 95%Cl: 0.95, 3.80) and albumin level (adjusted β: 0.51; 95%Cl: 0.07, 0.95).

Conclusion: Identified modifiable predictors of quality of life in chronic kidney disease and ESRD patients may enable future planning of interventions to improve quality of life.

Keywords: chronic kidney disease, quality of life, KDQOL-SF